KRT88P and hepatocellular carcinoma: To date, various HBV-encoded proteins, including HBX (Kong et al., 2019b; You et al., 2023b), HBC (Kong et al., 2020), PreS1 (Liu et al., 2017), and PreS2 (Teng et al., 2015), have been reported to participate in HBV-mediated HCC.