Based on the Gao cohort (Gao et al., 2019), GLUD1 gene levels were significantly lower in HBV-related HCC tissues than in adjacent tissues (Figure 6D), a negative correlation between GLUD1 gene level and tumor size in HBV-related HCC cohort was detected (Figure 6E), and low GLUD1 expression was significantly associated with poor OS, but not recurrence-free survival (RFS), in patients with HBV-related HCC (Figure 6F and G). The gene discussed is GLUD1; the disease is hepatocellular carcinoma.