When we analyzed the clinical aspects of rs852479 and rs1640233 FSCN1 and rs920778 HOTAIR genotypic frequencies among BC patients, we found that CC genotype of FSCN1 rs1640233 was significantly associated with developed tumor size and lymph node invasion (p-value = 0.04 and 0.02; respectively). The gene discussed is FSCN1; the disease is breast cancer.