C1q and TNF-related 1 (C1QTNF1, also known as CTRP1) expression is upregulated in metastatic cancer, high CTRP1 level is connected with poor prognosis, and CTRP1 knockout inhibits cell proliferation and invasion, and tumor growth [104]. The gene discussed is C1QTNF1; the disease is metastatic malignant neoplasm.