The following SNPs were associated with a better prognosis in glioma patients: rs10839 and rs9662128 in HPCAL4, rs10797484 in KCNK1/SLC35F3, rs1023793 in C3orf67/FHIT, rs3780471 in TRIM14, rs10745588 in LOC101928617/CLLU1OS, rs4133291 in MIR4318/MIR924HG, and rs56407818, rs55849754, and rs7247294 in LOC100420587/LINC00906 (all HR < 1, p < 0.05). This evidence concerns the gene HPCAL4 and central nervous system cancer.