Subgroup analysis in patients with cirrhosis showed HVPG to be an independent risk factor for poorer OS (HR, 1.28 [95% CI, 1.01–1.61]; P = 0.041) and TTR (HR, 1.46 [95% CI, 1.14–1.86]; P = 0.002). This evidence concerns the gene TTR and Cirrhosis.