In this study, we explored the roles of Hif-1α and its downstream molecule EGFR in pulmonary fibrosis mice and the APD group, suggesting that APD might regulate ferroptosis by inhibiting the Hif-1α-EGFR pathway, thereby alleviating pulmonary fibrosis (Figures 7(a) and 7(b)). This evidence concerns the gene HIF1A and pulmonary fibrosis.