To further elucidate the effects of early treatment with OBE on the asthma phenotype, we investigated its effect on a number of diverse pro-inflammatory molecules with different roles in asthma such as IL-1α and β, IL-5, IL-16, the colony-stimulating factors, GM-CSF, the chemokines eotaxin, RANTES, MIP-1α, MIP-1β, MCP-5 and also the anti-inflammatory IL-10. The gene discussed is IL5; the disease is asthma.