PRF1 and neoplasm: Aligned with their diverse targeting mechanisms and robust cytotoxicity, Allo/U15BCAR-NKT cells exhibited heightened expression of activation markers (i.e., CD69), and increased production of effector cytokines (i.e., IFN-γ) and cytotoxic molecules (i.e., Perforin and Granzyme B), compared with BCAR-T cells following co-culture with tumor cells (Figures 4H–4J and S6B).