SALL4 expression in CRC tissue and serum correlates with the degree of lymph node metastasis (LNM), differentiation degree, and staging, and patients with high SALL4 expression usually have a shorter mean survival time than those with low SALL4 expression (Hao et al. 2016; Moein et al. 2022; Liu et al. 2021; Abouelnazar et al. 2023b; Wu et al. 2017; Forghanifard et al. 2013). This evidence concerns the gene SALL4 and colorectal carcinoma.