KL and chronic kidney disease: Overall, there were statistically significant differences between non-CKD and CKD participants in terms of sex, age, race, educational attainment, BMI, smoking status, CVD, DM, hypertension, Klotho, TC, TG, WBC, Neu, Mono, SII, NLR, MLR, SIRI, PIV, eGFR, serum creatinine, uric acid and serum urea nitrogen (all P < 0.05).