However, when analyzing the correlation between KL expression and BUN, only KL expression in the CKD tubulointerstitium was negatively correlated with BUN (R =−0.3685, P < 0.0001) (Fig. 1L), while KL expression in the CKD glomeruli was not correlated with BUN (R =−0.1052, P = 0.2000) (Fig. 1K). The gene discussed is KL; the disease is chronic kidney disease.