Our data showed the overexpression of RAD51-AS1 in OvCA cells, and further function analyses showed the contributory effect of RAD51-AS1 on cell malignancy in OvCA cells in vitro, including proliferative, invasive, migratory, and EMT, as well as tumor growth in mouse models, supporting the oncogenic role of RAD51-AS1 in OvCA. This evidence concerns the gene RAD51 and neoplasm.