Interestingly, regardless of which non-sensitizer was used, there were two upregulated genes among AMs and epithelial cells associated with airway hyperresponsiveness and allergy (CCL3L1, GJD3), and among DCs, there were 5 upregulated genes in common also associated with airway allergy and inflammation (SOX9, UACA, CCDC88A, FOSL1, KIF20B) (Laulajainen-Hongisto et al. 2020; Jiang et al. 2021; Bao and Zhu 2022). This evidence concerns the gene CCL3L3 and allergic respiratory disease.