VEGFA and hepatocellular carcinoma: As an alternative to multi-kinase inhibitors such as sorafenib (SOR) or lenvatinib (LEN) for the treatment of HCC, the combination of atezolizumab, a fully humanized anti-programmed death-ligand 1 (PD-L1), and bevacizumab, a vascular endothelial growth factor (VEGF) targeting antibody (ATZ/BEV), was recently approved as first-line therapy, with a median overall survival benefit of 17 months [3].