The top 100 genes found to be co-expressed with CD74 were examined using GEPIA2.0, finding that the top five genes (HLA-DMA, HLA-DPA1, HLA-DPB1, HLA-DRA, and HLA-DRB1) were highly correlated with CD74 in most tumor types (Fig. 6C). Here, HLA-DRB1 is linked to neoplasm.