LINC01056 and hepatocellular carcinoma: Moreover, the mRNA and protein levels of PPARα were not significantly altered upon knockdown of Linc01056 in HCC cells, suggesting that Linc01056 does not directly regulate the transcription or the protein stability of PPARα and thus regulates the transcriptional activity of PPARα as an epigenetic regulator at the posttranscriptional level [34].