SCD and sunburn: Besides, ultraviolet (UV) absorption by the skin triggers not only local cutaneous injury but also secondary systemic changes, like the neuroendocrine homeostasis.[47] Peptides secretion has been regarded as a defense against UV in amphibians.[13] And the pharmacological inhibition of STING was recently reported to restrain UV‐induced skin injury.[48] Therefore, it's worthwhile to investigate whether the RIFSP‐2, targeting SCD1/ STING signal also serves for sunburn.