POU3F1 and Insulin resistance: We found genes related to regulation of actin cytoskeleton, insulin resistance, HIF‐1 signaling pathway, fructose and mannose metabolism, focal adhesion, endocrine resistance, ECM‐receptor interaction, cellular senescence, biosynthesis of unsaturated fatty acid, and adhesion junctions were significantly enriched in both IDH1 (Flag) and OCT6 peaks upon MPA treatment (Figure 6g).