CCNB1 and cancer: The analysis revealed that the CCNB1 expression levels were significantly linked with clinical stages in 12 cancer types, namely, LUAD, COAD, COADREAD, BRCA, ESCA, KIRP, KIPAN, KIRC, LUSC, LIHC, ACC, and KICH, with an upregulation mainly noted in later stages (stages III and IV) for LUAD, BRCA, KIRP, KIRC, LIHC, ACC, and KICH (Figure 4A).