NFKBIZ and neoplasm: Therefore, we could only try to reveal the direct effect of decreased NFKBIZ expression on HCC malignant behaviors in vivo, by comparing the tumor tissue from both sides of our xenograft mice with HepG2 or MHCC97H cells stably transfected with sh-NFKBIZ on the right dorsal side and those cells with sh-NC on the left side (Supplemental Fig. 3).