TERT and meningioma: In particular, mutations of the telomerase reverse transcriptase (TERT) promotor region as well as homozygous deletion of CDKN2A/B were frequently observed in higher-grade meningiomas and associated with poor survival [1, 17, 21, 24], thus designating any of such tumors to CNS WHO grade 3 irrespective of its histologic subtype [16].