Conversely, GGT5 demonstrated a notable reduction in invasive breast carcinoma (BRCA), cervical squamous cell carcinoma, and endocervical adenocarcinoma (CESC), kidney chromophobe (KICH), kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP), liver hepatocellular carcinoma (LIHC), pheochromocytoma and paraganglioma (PCPG), and uterine corpus endometrial carcinoma (UCEC) (all p < 0.05) (Fig. 1A). This evidence concerns the gene GGT5 and chromophobe renal cell carcinoma.