Among these, known CNVs included 1q21.1 recurrent microduplication, 7q11.23 duplication syndrome, 15q11.2 BP1-BP2 microdeletion, 16p11.2 microduplication syndrome, 22q11.2 deletion/duplication syndrome, Cat eye syndrome, and others. Here, IGFBP2 is linked to cat-eye syndrome.