The phenotypes with the strongest association with IL6R were aortic aneurysm (AA) (OR 0.92; 95% CI, 0.90–0.94) as well as a specific type of aortic aneurysm, abdominal aortic aneurysm (AAA) (OR, 0.89; 95% CI, 0.87–0.90), coronary atherosclerosis and ischemic heart disease (CHD) (OR, 0.96; 95% CI, 0.95–0.97) (Fig. 1). Here, IL6R is linked to triple-A syndrome.