Fibrosis-4 (FIB-4) index, calculated from three biochemical indices (aspartate aminotransferase (AST), alanine aminotransferase (ALT), and platelet count) and age, is a noninvasive marker for evaluating liver fibrosis and could provide accurate prediction for decompensation18,19. The gene discussed is GPT; the disease is Hepatic fibrosis.