Notably, also sera from patients suffering from autoimmune diseases, i.e., rheumatoid arthritis (n = 4), systemic lupus erythematosus (SLE) (n = 5), or cryoglobulinemia (CG) (n = 8) either did not or even negatively impact on CD32B or CCR5 trogocytosis (Figures 3B and S7C). Here, FCGR2B is linked to autoimmune disease.