We collected multiple GWAS studies, including UKB, FinnGen, and GWAS catalogue, and identified that TCF19 is significantly associated with multiple autoimmune diseases and human cancers, for example, type 1 diabetes and autoimmune thyroid diseases (P=1.0x10-23), cervical cancer (4.0x10-25) and lung cancer (5.0x10-19) (Table 1). This evidence concerns the gene TCF19 and type 1 diabetes mellitus.