TNF and hydrops fetalis: GO and KEGG enrichment analysis of 36 common target genes through the DAVID database showed that a total of 286 biological functions and 93 signaling pathways were annotated, and according to the enrichment results of KEGG pathways, inflammatory signaling pathways such as TNF signaling, IL-17 signaling, NF-kB signaling, TOLL-like receptors, and NOD-like receptors were enriched, suggesting that these bioinformatics functions and inflammatory signaling pathways are important mechanisms of action of SGC in the treatment of HF.