We also took the suitability for children into account, as some of the nucleic acid-induced autoimmune diseases are childhood-onset diseases, such as AGS and STING-associated vasculopathy with onset in infancy (SAVI) (Jeremiah et al., 2014; Liu et al., 2014). Here, STING1 is linked to STING-associated vasculopathy with onset in infancy.