AKT1 and pulmonary fibrosis: Taken together, our findings suggest that Gas6/Axl/Akt pathway possibly leads to the increased COX-2 transcriptional induction as well as PGE2 and PGD2 secretion to protect against the development of the EMT phenotype in ATII cells and the myofibroblast phenotype during BLM-induced lung fibrosis.