TGFB1 and pulmonary fibrosis: To confirm that the suppressive impacts of rGas6 on the EMT and fibroblast activation consequently prevent lung fibrosis, the levels of TGF-β and HGF, the major profibrotic and antifibrotic cytokines, respectively (Lee et al. 2012a, b), were examined following BLM treatment with or without rGas6.