ING1 and COVID-19: Notably, monocyte–NK interactions in these samples were also predicted to upregulate several genes involved in cell cycle regulation [CCNG2 (68), ING1 (69), PDCD4 (70), TENT5C (71)] (Fig. 2D), which contrasts with the genes involved in proliferation and apoptosis upregulated in severe COVID-19 patient NK cells (Fig. 2C).