As shown in Table 2, univariate logistic regression analysis showed that age, sex, SBP, hypertension history, diabetes history, CHD history, smoking history, drinking history, SBP, CRP, FPG, HbA1c, TC, LDL‐C, homocysteine, eGFR, uric acid, and NLR were significantly associated with CSVD. This evidence concerns the gene CRP and Hypertension.