Differential expression patterns of DRGs in the control group and COPD group were visualized through DEGs box plots, with COPD patients exhibiting high expression levels of genes such as SLC7A11, NCKAP1, and NUBPL (Figure 2A), and these results were further confirmed in a cigarette smoke‐induced COPD mouse model by qPCR (Supporting Information: Figure S1). Here, NUBPL is linked to chronic obstructive pulmonary disease.