Another study reported that compared with HCs, CD4+CD25+CD161+ T cell subsets significantly increased in the peripheral blood of pSS patients, and the proportion of IL‐17‐producing cells in CD161+ T cell was higher than that in CD161− T cell, and CD4+CD161+ T cells in peripheral circulation were related to the activity and severity of pSS disease.12 Here, CD4 is linked to peeling skin syndrome.