The investigation uncovered that VIRMA is highly expressed in several malignancies, such as hepatocellular carcinoma (HCC), kidney chromophobe, HNSCC, lung adenocarcinoma, lung squamous cell carcinoma, colorectal cancer, rectal adenocarcinoma, breast invasive carcinoma, kidney clear cell carcinoma, and cholangiocarcinoma. Here, VIRMA is linked to cholangiocarcinoma.