IGF2BP3 and neoplasm: Additionally, IGF2BP3 was positively related to tumor mutational burden (TMB) of LUAD, LGG, KIRC, HNSC, GBM, COAD, BRCA, ACC, THYM, SKCM, SARC, PAAD, OV, and LUSC, while negatively correlated with TMB of UVM (Figure 10D).