These functional pathways (or functional gene sets) include tumor inflammation signature, tumor proliferation signature, cellular response to hypoxia, EMT markers, angiogenesis, apoptosis, ECM related genes, DNA repair, inflammatory response, G2M checkpoint, PI3K_AKT_mTOR_pathway, MYC targets, P53_pathway, TGFβ, genes upregulated by reactive oxygen species (ROS), IL-10 anti-inflammatory signaling pathway, DNA replication, degradation of ECM, collagen formation, and ferroptosis related pathways. Here, TP53 is linked to neoplasm.