Recent research has shown that Dectin-1 signaling can prompt the release of pro-allergic chemokines and the secretion of mucus 72, drive the differentiation of regulatory T cells 73, and activate IL-17F signaling pathways 74, 75, suggesting that Dectin-1 has critical roles in not only the immune response but also in the development of allergic, immune-mediated, and neoplastic diseases 76. The gene discussed is CLEC7A; the disease is neoplasm.