Based on the analysis of survival data across 33 cancer types in TCGA and UCSC databases, we found that high expression of ASB6 was significantly associated with shorter disease-free interval (DFI), disease-specific survival (DSS), overall survival (OS), and progression-free interval (PFI) in adrenocortical carcinoma (ACC), liver hepatocellular carcinoma (LIHC), lung squamous cell carcinoma (LUSC), prostate adenocarcinoma (PRAD), and rectum adenocarcinoma (READ) (Figure 2A, C). The gene discussed is ASB6; the disease is rectum adenocarcinoma.