The multicenter study involving 138 prostate cancer (PCa) patients with biochemical recurrent (BCR) lesions, classified as progressive, mixed, or nonprogressive, utilized quantitative parameters (SUVmean, SUVmax, SUVpeak, volume) to quantify tumor response at a focal level following 68Ga-PSMA-11 PET scans. Here, FOLH1 is linked to Familial prostate cancer.