As shown in the tumor growth curves (Figure 7), the initial tumor volumes on day 0 for the sham, NC siRNA LPX + UTMC, and EGFR siRNA LPX + UTMC groups were similar (32.3±3.4 mm3, 34.4±3.3mm3 and 31.3±3.1mm3, respectively(p>0.05, ANOVA); on day 9, the tumor volume of mice in the EGFR siRNA LPX + UTMC group (323.8±56.0 mm3) was significantly smaller than the volume for sham (712.8±172.2 mm3) and NC siRNA LPX + UTMC (537.6±65.1mm3) groups (p<0.05 ANOVA; Student's t-test p<0.05 for EGFR siRNA LPX + UTMC vs. each control groups). Here, EGFR is linked to neoplasm.