SIRPA and neoplasm: Following anti-SIRPα treatment of B16.F10.GFP tumor-bearing mice (melanoma cells overexpressing GFP; Figure S4D), we detected a significant increase in the frequency of moDCs, M-MDSCs, and cDC2s sampling tumor-derived material as determined by detection of tumor-derived GFP signal within the cells (Figures 7C and S4E).