Briefly, conventional dendritic cells 1 (cDC1) can activate cytotoxic T cells,30 conventional dendritic cells 2 (cDC2) are key inducers of anti-tumor CD4 T cell responses,31 and monocyte-derived DCs (moDCs) can efficiently induce Treg activation and expansion.32 The gene discussed is CD4; the disease is neoplasm.