Among them, dihydromyricetin, a natural flavonoid extracted from vine tea, shown to restrain fibrosis in primary human and murine lung cells treated with TGF-b1 and in a bleomycin-induced mouse model of IPF by regulating the STAT3/pSTAT3/GLUT1 signaling pathway [75]. Here, TGFB1 is linked to idiopathic pulmonary fibrosis.