INS and urinary bladder cancer: KEGG pathway enrichment results mainly involved cancer-related signaling pathways, PI3K-Akt signaling pathway, cancer microRNAs, progesterone-mediated follicle maturation pathway, insulin resistance pathway, cellular senescence signaling pathway, bladder cancer signaling pathway, IL-17 signaling pathways, axon guidance signaling pathway, and gonadotropin-releasing hormone signaling pathway (Figure 8).