Notably, at baseline (T0: before FLX treatment), a significant reduction in TGF-β1 concentrations was observed in the PBMC culture media from young adult individuals with DS (19–35 years) compared to PBMCs from age- and sex-matched HC at T0 (Figure 7A, p < 0.05). The gene discussed is TGFB1; the disease is Dravet syndrome.