A highly statistically significant increase in HbA1c, fructosamine, fasting plasma glucose (FPG), fasting insulin level (FINS), and insulin resistance index (HOMA-IR), was detected in patients compared to controls (p < 0.001). Conversely, insulin sensitivity index (HOMA-IS) was statistically lower in patients compared to controls (p < 0.001). This evidence concerns the gene INS and Insulin resistance.