Therefore, when we considered with HLA-B*51:01:01 (OR = 3.033, 95% CI = 1.135–8.103, P-value = 0.027) and HLA-C*14:02:01(OR = 3.485, 95% CI = 1.339–9.065, P-value = 0.001) were associated with BD. This evidence concerns the gene HLA-B and Behcet disease.