Functional enrichment analysis yielded pathways related to response to cytokines, integrin-mediated signaling, and collagen trimers (Fig. 1C), with TIMP1 being a notable DEG (MFold Change, agitation. = 0.644, p = 3.0 × 10−5; MFC, affective = 0.748, p = 0.012; MFC, apathy. = 0.644, p = 1.1 × 10−5; MFC, psychosis. = 0.642, p = 1.1 × 10−5). Here, TIMP1 is linked to psychotic disorder.