We identified 7 T2D-DMPs with significant trans meQTL associations (P = 5 × 10−8, Supplementary Table S5) in NGB, OTX2, SLC16A3, ITPR1, TNIP1, and two intergenic regions (chr1:18057598 and chr11:44339522). Here, OTX2 is linked to type 2 diabetes mellitus.