OTX2 and type 2 diabetes mellitus: Of the 8 T2D-DMPs that had direct evidence for a genetic basis of the target MCC-seq CpG site, five (in OTX2, SLC16A3, B3GAT2, TNIP1 and intergenic region chr11:44339522) were also identified in the genetically-independent results from the T2D-discordant MZ twin analysis.