SPRED2 and type 2 diabetes mellitus: In addition, whilst not meeting nominal significance, 10 further T2D-DMPs showed the same direction of effect in the T2D association analysis (in cg02985292 (METTL26), cg01088070 (B3GAT2), cg10256249 (SPRED2), cg27175093 (OTX2), cg15989436 (TNIP), cg05468064 (chr22:46423445), cg21545390 (DLX6), cg15131789 (chr1:18057598), cg02400572 (NGB), cg08995368 (FSCN1)) and 2 further T2D-DMPs matched direction of effect in only the FBG analysis (in cg21545390 (DLX6), cg15131789 (chr1:18057598)).