Previous studies have demonstrated that DEHP binds to estrogenreceptor α (ERα), leading to carcinogenic potential andthe ability to influence cell proliferation and tumor metastasis.51,52 Studies are needed to fully understand the effects of DEHP on gastriccancer MKN45 cells expressing ERα and its specific role in influencingthe EMT-related process. The gene discussed is ESR1; the disease is neoplasm.