According to the KRAS phenotype, four CRC patients with transcriptome sequencing data were divided into the KRAS mutant group and the KRAS wild-type group to identify KRAS mutation-related DEGs, and we found that there were 77 KRAS mutation-related DEGs, among which 55 DGEs in the KRAS mutant group were significantly upregulated and 22 DEGs were significantly downregulated compared with the KRAS wild-type group, as shown in Fig. S1A and Table S1. Here, KRAS is linked to colorectal carcinoma.