The top 10 KEGG pathways enriched in DEGs of microglia were IL‐17 signaling pathway, oxidative phosphorylation, Parkinson's disease, Alzheimer's disease, Huntington's disease, thermogenesis, transcriptional misregulation in cancer, metabolic pathways, systemic lupus erythematosus, and alcoholism (Figure 4B). The gene discussed is IL17A; the disease is early-onset autosomal dominant Alzheimer disease.